BM (Soton), PhD (Soton), LMCHK, MRCS(London), FRCS(Ortho), FHKCOS

Clinical Assistant Professor

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ORCID iD: 0000-0002-1562-8883

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Kelvin Sin Chi Cheung is a specialist orthopaedic surgeon and clinician-scientist, serving as Clinical Assistant Professor in the Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong.

He earned his Bachelor of Medicine (2006) and PhD (2016) from the University of Southampton, England. His doctoral work investigated the role of microRNAs in skeletal stem cell differentiation, building deep expertise in molecular biology, stem cell biology, and musculoskeletal tissue engineering.

After qualification, Kelvin practised as an emergency medicine physician at a major trauma centre in southern England for eight years before relocating to Hong Kong in 2014 to pursue advanced orthopaedic training and research. He is a Fellow of the Royal College of Surgeons of Edinburgh (Orthopaedics) FRCSEd (Ortho), Member of the Royal College of Surgeons of Edinburgh (MRCSEd) and England (MRCS Eng), and Fellow of the Hong Kong College of Orthopaedic Surgeons (FHKCOS), having completed specialist training in 2025.

Kelvin’s research centres on the molecular pathophysiology of bone tumours, with particular emphasis on chondrosarcoma, grade-specific ER stress targeting, and novel therapeutic vulnerabilities using patient-derived xenograft models and single-cell transcriptomics. He also leads work in osteo-sarcopenia and cutting-edge tissue engineering, including 3D bioprinting for meniscal regeneration utilising developmentally primed stromal cells. His integrated approach spanning translational biofabrication, stem cell applications, and oncology addresses major orthopaedic challenges. Supported by competitive grants such as the Health and Medical Research Fund (HMRF) for ER stress therapeutics in chondrosarcoma and the Research Grants Council (RGC) for progenitor cell characterisation in tumours, his work is reflected in high-impact publications, including key papers in Arthritis & Rheumatism, Rheumatology International, and Communications Biology (Springer Nature).

Drawing from extensive clinical experience in orthopaedics, sports medicine, and musculoskeletal oncology, Kelvin seamlessly bridges laboratory discovery and surgical practice, mentoring trainees and spearheading innovative research programmes at HKU.